Juglanin improves lipid metabolism disorder, liver injury, and intestinal integrity in nonalcoholic fatty liver mice
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چکیده
منابع مشابه
Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome. Berberine (BBR) exerts anti-hyperglycemic and anti-dyslipidemic effects and can also ameliorate NAFLD. Thus, BBR might exert its therapeutic effect on NAFLD by improving glucolipid metabolism. Here, we investigated the aspects and extent to which glucolipid metabolism were a...
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Nonalcoholic fatty liver disease (NAFLD) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. So changing in life style and interventions on obesogenic environment is cornerstone of NAFLD therapy in obese children. Some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...
متن کاملLipoprotein metabolism in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD), an escalating health problem worldwide, covers a spectrum of pathologies characterized by fatty accumulation in hepatocytes in early stages, with potential progression to liver inflammation, fibrosis, and failure. A close, yet poorly understood link exists between NAFLD and dyslipidemia, a constellation of abnormalities in plasma lipoproteins including ...
متن کاملAltered Hepatic Lipid Metabolism Contributes to Nonalcoholic Fatty Liver Disease in Leptin-Deficient Ob/Ob Mice
Nonalcoholic fatty liver disease (NAFLD) is strongly linked to obesity, insulin resistance, and abnormal hepatic lipid metabolism; however, the precise regulation of these processes remains poorly understood. Here we examined genes and proteins involved in hepatic oxidation and lipogenesis in 14-week-old leptin-deficient Ob/Ob mice, a commonly studied model of obesity and hepatic steatosis. Obe...
متن کاملthe relationship between intestinal motility and interstitial cells of cajal in nonalcoholic fatty liver mice
background nonalcoholic fatty liver disease (nafld) is the most common cause of chronic liver disease in western world. however, nafld shows an increasing trend in china every year, which has attracted the attention of national health authorities. the previous studies have shown that nafld caused severe gastrointestinal motor disorders, but little is known about the interstitial cells of cajal ...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2020
ISSN: 2219-2859
DOI: 10.11569/wcjd.v28.i4.113